Biopharmaceutical drugs have revolutionized the treatment of a broad spectrum of diseases and are increasingly used in nearly all branches of medicine. Biopharmaceuticals are highly specific and efficacious. However, they cannot be manufactured using traditional approaches because of their size and complex structure. Instead, they need to be produced in living organisms, making the manufacturing processes complicated. Biopharmaceutical products are created in upstream bioprocessing, from cell line development and cultivation to the expansion of the cells.
By adopting modern Timegated® Raman Technology, you can make a significant contribution to improvements in bioprocess monitoring and control. The technology provides real-time understanding of what is happening in the process and helps manage risks throughout the process.
In bioprocesses, many types of parameters can be analyzed. You can measure traditional parameters such as pH, temperature, and dissolved oxygen. When using Timegated® Raman Technology, you can also monitor biochemical parameters, such as nutrients (e.g. glucose concentrations), metabolites (e.g. lactate concentrations), amino acids, proteins, cell viability and biomass. Therefore, you gain access to all this data for analysis, allowing you to map the complex relationships between material attributes, cell media and process parameters.
